Patient Safety and Quality Improvement
 Modules  Module 5: Evidence-Based Medical Practice

Levels of Evidence
Systematic Review

Definition
A Systematic Review (SR) is an analysis conducted by a group of investigators who perform an extensive search for all individual randomized controlled trials conducted in a given area. Investigators then try to combine the data from all the multiple trials into one larger analysis. Ideally, this will create more statistical power and provide stronger conclusions.

  • Advantages: Has the potential to provide highly valid and useful evidence.
  • Disadvantages: If the studies that are combined for analysis aren’t similar (this is called the amount of homogeneity), the conclusions from the analysis may not be valid or useful.
 
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